Respiratory Insufficiency Clinical Trial
The failure of extubation in pediatric resuscitation is most often described as the need for
reintubation within 48 hours after extubation. The failure rate of extubation in pediatric
intensive care varies in the literature there is between 4 and 22% failures. These failures
result in increased mortality, morbidity with a use of larger tracheostomy, a prolonged
residence time. The extubation is codified in adult resuscitation and tends to be
increasingly in pediatric resuscitation. In the pediatric intensive care unit of
Hautepierre, a extubation protocol already exists for some time, and was prepared to go. the
current literature data. It allows the harmonization of practices in service (previously
left to the discretion of each doctor).
The investigators are looking to see if the protocol used systematically in the service
enables a reduction in the incidence of occurrence of failures of extubation.
Status | Recruiting |
Enrollment | 70 |
Est. completion date | July 2017 |
Est. primary completion date | July 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 18 Years |
Eligibility |
Inclusion Criteria: - Children hospitalized in pediatric intensive care, under 18 years, intubated, ventilated for more than 2 hours and for which planning extubation or intubated children for whom an unplanned extubation just happened. - Children whose holding parental authority are not opposed to the use of clinical data from their child for research purposes. Exclusion Criteria: - Refusal to participate in the study |
Country | Name | City | State |
---|---|---|---|
France | Service de Reanimation Pediatrique Specialisee - S. Continue | Strasbourg | F |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Strasbourg, France |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Failure of extubation | need for a new intubation within the first 48 hours after extubation |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05904652 -
High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties
|
N/A | |
Completed |
NCT04030208 -
Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation
|
N/A | |
Recruiting |
NCT03697785 -
Weaning Algorithm for Mechanical VEntilation
|
N/A | |
Recruiting |
NCT02989051 -
Fluid Restriction Keeps Children Dry
|
Phase 2/Phase 3 | |
Completed |
NCT02930525 -
Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation
|
N/A | |
Recruiting |
NCT02539732 -
Prediction of Outcome of Weaning From Mechanical Ventilation Using the Electrical Activity of the Diaphragm
|
||
Enrolling by invitation |
NCT02290236 -
Monitored Saturation Post-ICU
|
N/A | |
Completed |
NCT02056119 -
RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
|
N/A | |
Terminated |
NCT01583088 -
Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation
|
Phase 3 | |
Withdrawn |
NCT00990119 -
High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)
|
N/A | |
Completed |
NCT00741949 -
Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol TCI in Patient With AHRF
|
Phase 3 | |
Completed |
NCT01411722 -
Electrical Activity of the Diaphragm During the Weaning Period
|
Phase 2 | |
Recruiting |
NCT00339053 -
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
|
Phase 4 | |
Recruiting |
NCT00187434 -
Comparison of Two Methods of Continuous Positive Airway Pressure (CPAP) to Support Successful Extubation of Infants of Birth Weights ≤ 1500 Grams (C2CPAP)
|
N/A | |
Completed |
NCT02687802 -
Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation
|
||
Not yet recruiting |
NCT05906030 -
Diaphragm Dysfunction and Ultrasound Perioperatively
|
||
Completed |
NCT03850977 -
Is There an Association Between Chronic Pancreatitis and Pulmonary Function
|
||
Completed |
NCT02845375 -
Effect of Neuromuscular Blockade and Reversal on Breathing
|
Phase 4 | |
Recruiting |
NCT03309423 -
Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU?
|
N/A | |
Completed |
NCT04115969 -
Outcome After Non-invasive Ventilation.
|