Paravertebral Block With Brachial Plexus Block for Upper Arm Arteriovenous Fistula Surgery

Regional Anesthesia Success Clinical Trial

Official title:

The Effectiveness of Thoracic Paravertebral Block in Improving the Anesthetic Effects of Regional Anesthesia for Upper Extremity Arteriovenous Fistula Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04720079
• Other study ID #: 20-2303
• Status: Completed
• Phase: N/A
• Start date: November 15, 2020
• Est. completion date: February 15, 2022

Study information

• Verified date: November 2021
• Source: University of North Carolina, Chapel Hill
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary goal of this quality improvement project is to find the optimal surgical conditions for patients undergoing upper arm arteriovenous graft surgery. Currently, there are two anesthetic techniques used in clinical practice. The goal is to standardize future practice and improve the care of patients postoperatively. The two techniques used in conjunction with a brachial plexus block are paravertebral nerve block and subcutaneous infiltration.

Description:

This study is designed to test the null hypothesis that paravertebral nerve block or subcutaneous infiltration provide similar operating conditions when combined with supraclavicular nerve block for upper arm arteriovenous fistula surgery. The results will help determine which approach to use and guide future research in this area.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 63
• Est. completion date: February 15, 2022
• Est. primary completion date: February 15, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients (>18 years) undergoing upper limb arteriovenous fistula surgery at UNC Chapel Hill hospital

Exclusion Criteria:

• Contraindication to regional anesthesia
• Significant peripheral neuropathy or neurological disorder of the upper extremity
• Cognitive or psychiatric condition that will interfere with patient assessment

Related Conditions & MeSH terms

• Arteriovenous Fistula
• Fistula
• Regional Anesthesia Success

Intervention

Procedure:
• Subcutaneous infiltration of intercostobrachial nerve
Preoperative subcutaneous infiltration of intercostobrachial nerve with 10ml of 0.5% ropivacaine
• T2 paravertebral nerve block
Preoperative ultrasound guided T2 paravertebral nerve block with 10ml of 0.5% ropivacaine

Locations

Country	Name	City	State
United States	University of North Carolina at Chapel Hill	Chapel Hill	North Carolina

Sponsors (1)

Lead Sponsor	Collaborator
University of North Carolina, Chapel Hill

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Participants with Successful Regional Anesthesia	Success is considered a regional anesthetic without rescue analgesic medications (including surgeon administered local anesthetic) or conversion to general anesthesia	By end of surgery