Distilled Water Clinical Trial
Official title:
The Efficacy of Distilled Water vs Mitomycin C as a Single Dose Immediate Instillation After Transurethral Resection of Intermediate Risk, Recurrent Superficial Bladder Cancer
The purpose of this study is to compare and evaluate the efficacy of distilled water vs Mitomycin C on preventing the recurrences of intermediate risk group recurrent superficial bladder cancer administered as a single dose immediate instillation after complete Transurethral Resection(TUR) of the tumor.
We plan to administer 200ml of distilled water as a single peroperative instillation and
block the catheter for 2 hours to our eligible recurrent superficial bladder cancer patients
who were in our follow-up schedule since 2002.
We plan to look over the histories of the same patients in terms of the pathologies,
recurrence patterns, the presence of peroperative intracavitary therapy after their previous
TURs for recurrences.
So we shall compare the effectiveness of MMC and distilled water on reducing the recurrences
over the same patient pool.
The patients will be scheduled for a follow-up program after TUR as;
- cystoscopy
- urine cytology
- bladder wash cytology for the probability of recurrence for 2 years to see if there is
any difference in the recurrence patterns after instillation with distilled water vs
MMC.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Caregiver), Primary Purpose: Prevention