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Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer

Recurrent Salivary Gland Cancer Clinical Trial

Official title:
Phase II Trial of Eribulin for Locally Advanced Refractory or Metastatic Salivary Gland Cancers

Clinical Trial Summary

Researchers are doing a research study to examine the use of eribulin (eribulin mesylate) in patients with salivary gland cancer. Researchers want to know if eribulin is safe and effective in treating salivary gland cancer.

Clinical Trial Description

PRIMARY OBJECTIVES:

I. Evaluate the response rate of eribulin per Response Evaluation Criteria In Solid Tumors (RECIST) in patients with locally advanced refractory or metastatic salivary gland cancer (SGC).

SECONDARY OBJECTIVES:

I. Determine the safety and toxicity of eribulin in patients with locally advanced refractory or metastatic SGC.

II. Evaluate the duration of response and time-to-progression.

OUTLINE:

Patients receive eribulin mesylate intravenously (IV) over 2-5 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up at 30 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01613768
Study type Interventional
Source University of Washington
Contact
Status Completed
Phase Phase 2
Start date May 8, 2012
Completion date August 23, 2017
View Details
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