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Recurrent Low Back Pain clinical trials

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NCT ID: NCT03031938 Not yet recruiting - Osteoarthritis Clinical Trials

Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies

Start date: October 31, 2017
Phase: Phase 3
Study type: Interventional

A4091065 is a multicenter, prospective, cohort study with enhance physical an neurodevelopmental surveillance to characterize the outcomes related to the development of infants up to the age of 15 months who were potentially exposed to tanezumab, placebo or comparator via maternal exposure or in utero in any tanezumb study.

NCT ID: NCT02487368 Completed - Clinical trials for Chronic Low Back Pain

Effects of a Mechanical Needle Stimulation Pad on Chronic Low Back Pain

NRM_2009
Start date: October 2009
Phase: N/A
Study type: Interventional

The needle stimulation pad is a self-care device, which has been promoted for pain control and well-being. The aim of the study was to test the efficacy of the pad for chronic/recurrent low back pain treatment. Patients with non-specific chronic or recurrent low back pain were selected from a large health insurance company database and advised to use the pad daily for two weeks; outcomes were assessed at baseline, weeks 2 and 14. Primary outcome measure was pain intensity at week 2; secondary outcome measures included the Oswestry disability index (ODI), health-related quality of life (SF-36), the fear avoidance beliefs questionnaire (FABQ), analgesic medication consumption and safety.

NCT ID: NCT02224183 Completed - Clinical trials for Recurrent Low Back Pain

Yoga vs. Education for Veterans With Chronic Low Back Pain

Start date: March 2015
Phase: N/A
Study type: Interventional

Chronic low back pain (cLBP) is the most common pain condition in the military, causing substantial physical and psychological suffering, reduction in force readiness, and high economic cost. Yoga has been studied in 10 RCTs in civilian populations with cLBP suggesting it may be effective in reducing pain intensity, improving back-related function, and lowering pain medication use. Multiple differences exist between civilian and military populations with cLBP, making it necessary to adapt and test yoga for cLBP in military populations. This study's primary aim is to evaluate the effectiveness of yoga for reducing pain in military personnel and Veterans with cLBP through a structured, reproducible 12-week series of hatha yoga classes, supplemented with home practice, compared to an education group. Additionally, the enormous mental health burden often shouldered by returning military personnel presents another important distinguishing factor. Thus, the study's secondary aim is to assess yoga's capacity to reduce post-traumatic stress symptoms (PTSS). The third aim is to evaluate the cost-effectiveness of yoga for cLBP at 3 months and 6 months from the perspective of the provider, the Veteran, and the Veterans Health Administration. The fourth and final aim is to evaluate the effect of back pain and yoga on marital and family functioning. The proposed RCT will (1) establish a structured reproducible yoga protocol uniquely suited to Veterans populations with cLBP; (2) develop web-based delivery systems to assist Veterans in yoga home practice; (3) increase our knowledge of the feasibility and impact of yoga for Veterans' cLBP and psychological comorbidities. These results will help determine whether yoga is an effective modality for addressing cLBP in a Veteran population.

NCT ID: NCT02112760 Completed - Clinical trials for Recurrent Low Back Pain

Specific Stabilization Exercise With Ultrasound Feedback For Patient With Recurrent Low Back Pain

Start date: June 2011
Phase: N/A
Study type: Interventional

1. Specific aim 1:Identify factors that influence muscle performance by use of ultrasound imaging. Hypothesis: Gender, age, and BMI affect the muscle performance of deep trunk muscles. 2. Specific aim 2. To compare the performance of trunk deep muscles (transversus abdominis and multifidus) and the sensation and pain thresholds of patients with recurrent low back pain with asymptomatic subjects. Hypothesis: patients with recurrent low back pain have: (A) less activation of the transversus abdominis and multifidus, (B) peripheral and central sensitization, with decreased sensation and pain thresholds in the lumbar and foot areas. 3. Specific aim 3. To determine the performance of the transversus abdominis and multifidus, and the sensation and pain thresholds by use of ultrasound feedback training in asymptomatic adults, and to compare these results with the traditional training protocols for trunk stabilization. Hypothesis: Specific stabilization exercise using ultrasound feedback training is more effective in activating deep trunk muscles and increasing sensation and pain thresholds than the traditional stabilization training protocol in asymptomatic adults. 4. Specific aim 4. To determine the performance of the transversus abdominis and multifidus, and the sensation and pain thresholds by using the ultrasound feedback training in adults with low back pain, and to compare these results with the traditional training protocols for trunk stabilization. Hypothesis: Specific stabilization exercise using ultrasound feedback training is more effective in activating deep trunk muscles and increasing sensation and pain thresholds than the traditional stabilization training protocol in adults with low back pain.

NCT ID: NCT01539863 Completed - Clinical trials for Chronic Low Back Pain

Chiropractic Maintenance Care of Persistent or Recurrent Low Back Pain

Start date: March 2012
Phase: N/A
Study type: Interventional

As low back pain is often a recurrent and sometime persistent problem, research into prevention is important. Chiropractors have traditionally treated patients with maintenance care, which means that patients are seen on a regular basis to prevent recurrences or to stop a persistent problem getting worse. However, it is not known if this has the expected effect. This study will test the effectiveness of the maintenance care approach. Patients with recurrent or persistent low back pain will be treated in accordance with two different models. The first model is the maintenance care model, meaning that chiropractors will see the patient on a regular basis, regardless symptoms. The other model means that patients should be treated patients only when they themselves experience symptoms bad enough to seek care. After one year, it will be possible to see if there has been any difference between the groups in terms of pain, disability, quality of life and total number of treatments over the study period and to investigate if there is any difference in the cost-effectiveness between the two treatment models.Thus, the study hypothesis is that there is no difference between the two models regarding the number of days with pain. This study will be a multi-centre trial, and as part of the study, it will be necessary to formalize a network of research clinics all over Sweden in which participating chiropractors accept to perform complex data collection. This network will then have the expertise and potential to perform future clinical studies together with networks in other countries, allowing large clinical trials across countries.

NCT ID: NCT00393354 Completed - Clinical trials for Recurrent Low Back Pain

Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-041)

Start date: April 2000
Phase: Phase 3
Study type: Interventional

Study the effect of etoricoxib 60 mg and 90 mg compared to placebo to treat chronic low back pain.

NCT ID: NCT00393211 Completed - Clinical trials for Recurrent Low Back Pain

Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-042)

Start date: April 2000
Phase: Phase 3
Study type: Interventional

Study the effect of etoricoxib 60 mg and 90 mg compared to placebo to treat chronic low back pain.