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Recurrent Grade III Glioma clinical trials

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NCT ID: NCT04323046 Recruiting - Glioblastoma Clinical Trials

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Start date: October 2, 2020
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects of nivolumab before and after surgery in treating children and young adults with high grade glioma that has come back (recurrent) or is increasing in scope or severity (progressive). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.