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Recurrent Depressive Disorder clinical trials

View clinical trials related to Recurrent Depressive Disorder.

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NCT ID: NCT02661061 Recruiting - Depression Clinical Trials

Ketamine for Relapse Prevention in Recurrent Depressive Disorder

KINDRED
Start date: December 2015
Phase: Phase 1
Study type: Interventional

Randomised, controlled, parallel-group, pilot clinical trial of ketamine vs. midazolam for depression relapse prevention in persons at high risk. The main purpose of the pilot study is to assess trial processes to help inform a future definitive trial.

NCT ID: NCT02016261 Completed - Clinical trials for Recurrent Depressive Disorder

Study to Evaluate Cognitive Functioning in Remitted Depression During Treatment With Fluvoxamine

Start date: December 2013
Phase: Phase 4
Study type: Interventional

Open label, non-comparative, prospective study to evaluate cognitive functioning in remitted depression outpatients during long-term preventive treatment with Fluvoxamine (Fevarin®)

NCT ID: NCT01973478 Active, not recruiting - Clinical trials for Major Depressive Disorder

Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression

STHYM
Start date: May 2014
Phase: Phase 3
Study type: Interventional

Major depressive disorders are real public health issues in terms of diagnosis and treatment. Some forms of depression are chronic and resistant to treatment (TRD). In these forms suicide risk is important. Patients with TRD are potential candidates for neurosurgical interventions to treat depression. However, psychosurgery interventions based upon lesions, showed their limitations related to 1. the large variability in neurosurgical gestures, 2. their side effects, and of course 3. the irreversible damage caused by the surgery. Thus, deep brain stimulation (DBS) could represent an opportunity for patients suffering from TRD. Our preliminary study based upon the stimulation of the accumbens nucleus showed encouraging results. The investigators have thus planned a randomized controlled trial versus sham stimulation to confirm the therapeutic value of nucleus accumbens DBS.

NCT ID: NCT01722344 Active, not recruiting - Clinical trials for Bipolar Affective Disorder

Improving Work Outcome for People With Severe Mental Illness

Start date: October 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy of IPS in Denmark and compare effects of 1. Individual Placement and Support (IPS) vs. 2. IPS + cognitive remediation and work-related social skills training vs. 3. standard intervention, among individuals with severe mental illness.