Q Fever Clinical Trial
Official title:
Prevalence and Risk Factors for Coxiella Burnetii Seropositivity (Q Fever) Among Adults in Western France
Diseases naturally transmitted between animals and humans (zoonoses) are one of the leading
causes of emergence or re-emergence of human infectious diseases. Non-foodborne zoonoses are
commonly transmitted to human directly by contact with infected animals or contaminated
environment. People working with animals such as farmers and veterinarians are particularly
at risk of infection. Some zoonoses can also be transmitted indirectly thought the air and
therefore can affect the general population. Example is Q fever, a disease caused by Coxiella
burnetii, a bacterium highly resistant in the environment.
In Western France, Q fever is endemic in cattle herds. To improve human zoonotic disease
surveillance, the investigators will conduct a population based study in this area.
The aims of the study are:
1. To assess seroprevalence of Coxiella burnetii infection among general population,
farmers and veterinarians in Western France
2. To identify risk factors for Coxiella burnetii seropositivity in these populations
In order to estimate seroprevalence and risk factors for Coxiella burnetii infection in
humans, the investigators will conduct a cross-sectional study in three groups:
- blood donors at blood donation organizations (general population)
- beef and dairy cattle farmers
- veterinarians involved in a rural practice
All the participants in the study will provide a blood sample and will fill in a
questionnaire.
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