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Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment

Pulmonary Arterial Hypertension Clinical Trial

Official title:
Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment

Clinical Trial Summary

Evaluation of the effect of CPAP (continuous positive airway pressure ) treatment in PAH (pulmonary arterial hypertension) and CTEPH (chronic thromboembolic pulmonary hypertension) patients suffering from sleep disordered breathing.

Clinical Trial Description

The primary endpoint of the study is to evaluate the effect of CPAP therapy on pulmonary vascular resistance in PAH and CTEPH patients suffering from sleep disordered breathing. The secondary endpoints are the effect of CPAP on right atrium and right ventricle diameter and ejection fraction measured by echocardiography, 6 minutes walk distance, NYHA class, QOL, endothelial function, sympathetic activity and prognosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02583906
Study type Interventional
Source Universitaire Ziekenhuizen KU Leuven
Contact
Status Terminated
Phase N/A
Start date April 2014
Completion date May 2019
View Details
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