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Clinical Trial Summary

Pilot study to determine the therapeutic effect of two prarallel groups treated with either Riciguat or Macitentan, evaluated by the change in systolic and diastolic RV function within 12 weeks after first drug intake in order to plan a larger Phase II study.


Clinical Trial Description

In this multi-center, randomized, open pilot study the therapeutic effect of two prarallel groups treated with either Riciguat or Macitentan shall be determined by evaluating the change in systolic and diastolic RV function within 12 weeks after first drug intake in order to plan a larger Phase II study.The method used to determine the RV function will be the "Conductance Method". ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03362047
Study type Interventional
Source University of Giessen
Contact Tello Khodr, MD
Phone +49-(0)641-985-56087
Email Khodr.Tello@innere.med.uni-giessen.de
Status Recruiting
Phase Phase 2
Start date March 1, 2018
Completion date February 1, 2020

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