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NCT01429870 Clinical Trial

Steroids Added to Dithranol and Narrow Band UVB(Ultraviolet B) (UVBnb) in Psoriasis

Psoriasis Clinical Trial

— DIPSO  

Official title:
A Phase IV, Randomized, Double Blind, Placebo Controlled, Single-center Study of the Impact of Topical Steroids on Narrow Band UVB (Ultraviolet B) and Dithranol Combination Treatment of Psoriasis (DIPSO)

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT01429870
Other study ID # DIPSO
Secondary ID KEK-ZH 2010-0171
Status Withdrawn
Phase Phase 4
First received
Last updated
Start date August 2011
Est. completion date August 2016

Study information
Verified date July 2018
Source University of Zurich
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Objective(s):

(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.

(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).

- Trial with medicinal product

Description:

(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.

(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).

- Trial with medicinal product

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date August 2016
Est. primary completion date August 2016
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion criteria:

- Moderate to severe psoriasis of the chronic-plaque and / or guttata type

Exclusion criteria:

- Participation in a Goeckerman therapy regimen within 6 months previous to the present study

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Steroid active treatment
Triamcinolone in unguentum leniens 0.1%

Locations
Country Name City State
Switzerland University Hospital Dermatology Department Zurich

Sponsors (1)
Lead Sponsor Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Relapse 50% PASI after treatment, time to PASI 75% on treatment Relapse 50% PASI after treatment, time to PASI 75% on treatment 2 years
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