Clinical Trials Logo

Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

Filter by:

NCT ID: NCT03536065 Recruiting - Prostate Cancer Clinical Trials

Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery

ORIOLES
Start date: August 1, 2017
Phase: Phase 4
Study type: Interventional

ORIOLES is a pre-post study designed to improve quality of opioid prescribing and use after discharge for patients undergoing urologic surgery. The study will initially focus on a pre-defined cohort of patients undergoing radical prostatectomy. After the predefined study period and results are obtained, the intervention may be applied to all urologic surgeries based on the degree of improvement demonstrated by the study.

NCT ID: NCT03533946 Not yet recruiting - Prostate Cancer Clinical Trials

Rucaparib in Nonmetastatic prOstAte With BRCAness

ROAR
Start date: July 2018
Phase: Phase 2
Study type: Interventional

This is a single arm, open label, phase II trial to assess efficacy of rucaparib.

NCT ID: NCT03532308 Not yet recruiting - Prostate Cancer Clinical Trials

Nutrition and Prostate Cancer

Start date: September 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy of Fermented Soy vs. placebo in 72 adults with localized prostate cancer prior to radical prostatectomy.

NCT ID: NCT03531099 Not yet recruiting - Prostate Cancer Clinical Trials

Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer

HIFUSA
Start date: July 1, 2018
Phase: Phase 3
Study type: Interventional

The percentage of malignant prostate tumors detected very early is constantly increasing and the number of well differentiated tumors, with small volume and low risk of progression increases. When a tumor of this type is identified, radical prostatectomy remains the reference treatment, but this treatment is not without side effects. Active surveillance is a strategy which aims at detecting an early development of the cancerous disease in order to propose curative treatment in a timely manner and thus improve specific survival. Patients are therefore re-evaluated each year by rectal examination, PSA (Prostate-Specific Antigen) assay. Active surveillance remains difficult to manage psychologically for both the patient and the practitioner, because of the lack of treatment on the one hand and a rate of non-curable cancers close to 50% when signs of progression trigger a radical treatment. The aim of the focal treatment HIFU (High Intensity Focused Ultrasound) is to destroy the cancer without causing side effects in contrast to radical treatments. It is in this sense that it is positioned both as an alternative to radical surgery and as an alternative to active surveillance.

NCT ID: NCT03529643 Recruiting - Prostate Cancer Clinical Trials

Effect of Anesthetic Method on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy

Start date: May 24, 2018
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the effect of anesthetic method on the optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic prostatectomy.

NCT ID: NCT03526510 Recruiting - Prostate Cancer Clinical Trials

Hypofractionated Boost vs Conventionally Fractionated Boost for Localized High Risk Prostate Cancer

Start date: June 2011
Phase: N/A
Study type: Interventional

Randomized trial comparing 2 external beam radiotherapy fractionation schemes in patients with localized high risk prostate cancer. Primary endpoint is acute toxicity.

NCT ID: NCT03525652 Recruiting - Prostate Cancer Clinical Trials

Therapeutic Vaccine Plus PD-1 Knockout in Prostate Cancer Treatment

Start date: February 22, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This study is to evaluate the safety and efficacy of a therapeutic vaccine in combination with PD-1 knockout T cells in the treatment of advanced prostate cancer.

NCT ID: NCT03525288 Recruiting - Prostate Cancer Clinical Trials

PSMA-PET Guided Radiotherapy

PSMA-PETgRT
Start date: May 15, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

PSMA PET/CT has demonstrated higher sensitivity in detecting metastases than current imaging standard of care (CT and bone scan). [18F]DCFPyL is a promising high-sensitivity second generation PSMA-targeted urea-based PET probe. The hypothesis is that definitive radiotherapy (RT) informed by PSMA-PET findings will lead to improved cancer control outcomes compared to RT guided by conventional staging only. This study utilizes cmRCT design in companion to PERA (Partnership initiative for the Evaluation of technological innovation in Radiotherapy).

NCT ID: NCT03524391 Completed - Prostate Cancer Clinical Trials

Effect of Yoga Counselling on Quality of Life and Psychological Outcomes of Prostate Cancer Patients

Start date: February 12, 2016
Phase: N/A
Study type: Interventional

Cancer is second leading cause of death worldwide. The psychological issues are related to all stages of the disease affecting outcome of treatment and overall quality of life. The study evaluated the effectiveness of yoga counselling among prostate cancer patients on their quality of life and psychological outcomes.

NCT ID: NCT03520478 Not yet recruiting - Prostate Cancer Clinical Trials

A Study of SHR3680 in Treating Patients With Hormone Sensitive Prostate Cancer

Start date: May 30, 2018
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the safety and efficacy of SHR3680 with bicalutamide in the treatment of patients with hormone sensitive prostate cancer.