PRETERM DELİVERY and MYOCINE BINDING PROTEIN C LEVELs

Preterm Clinical Trial

Official title:

Can First Trimester Serum Myocine Binding Protein c Level Predict Preterm Birth

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05513768
• Other study ID #: GaziosmanpasaTREHKHD
• Status: Completed
• Start date: January 1, 2022
• Est. completion date: October 30, 2022

Study information

• Verified date: November 2022
• Source: Gaziosmanpasa Research and Education Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY.

SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.

Description:

IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY.

SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.A TOTAL OF 90 WOMEN WERE PLANNED TO INCLUDE 45 STUDY 45 CONTROL GROUP IN THE STUDY.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: October 30, 2022
• Est. primary completion date: October 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• being pregnant in the first trimester

• be between 18-40 years old

Exclusion Criteria:

• no history of preterm birth

• being pregnant with assisted reproductive techniques

• having a multiple pregnancy

• have cervical insufficiency

Related Conditions & MeSH terms

• Premature Birth
• Preterm

Intervention

Diagnostic Test:
• level of myosin binding protein c in serum
Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.

Locations

Country	Name	City	State
Turkey	Gaziosmanpasa Training and Research Hospital	Istanbul	Gaziosmanpasa

Sponsors (1)

Lead Sponsor	Collaborator
Gaziosmanpasa Research and Education Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	detection of prediction value of serum mbpc levels in preterm delivery	identifying prediction value of first trmester serum mbpc levels by comparing by serum levels of mbpc in groups	10 mounths