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Clinical Trial Summary

Preeclampsia is a frequent pathology. His etiology is doubtful.

Targets :

The study target is to identify a risk of preeclampsia group obtained with transcriptom analysis from circulating peripheric cells.

Design:

Multidisciplinary study (Gynaecology-Obstetric, Immunology, North CIC).

The study of the transcriptional history of peripheral blood cells of 2patients groups:

- A patient group with a preeclampsia before 34 SA

- A patient group with a normal pregnancy paired on main confusion factors. Blood sampling will be collected at the diagnosis and 8 weeks after delivery.

Results and perspectives

- Obtain a transcriptionnal signature of preeclampsia

- To identify new mechanism of the disease

- Identification of a specific transcriptom analysis with the comparison after delivery For long-term, the target is to identify risk patient in order to conduct easily preventive clinical trials in preeclamsia (primary prevention) and to consider a specific follow-up for risk patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01914809
Study type Interventional
Source Assistance Publique Hopitaux De Marseille
Contact florence bretelle
Email florence.bretelle@ap-hm.fr
Status Recruiting
Phase N/A
Start date June 15, 2011
Completion date January 25, 2021

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