Preeclampsia Clinical Trial
Official title:
Micro Array Analysis in Preeclampsia
Preeclampsia is a frequent pathology. His etiology is doubtful.
Targets :
The study target is to identify a risk of preeclampsia group obtained with transcriptom
analysis from circulating peripheric cells.
Design:
Multidisciplinary study (Gynaecology-Obstetric, Immunology, North CIC).
The study of the transcriptional history of peripheral blood cells of 2patients groups:
- A patient group with a preeclampsia before 34 SA
- A patient group with a normal pregnancy paired on main confusion factors. Blood sampling
will be collected at the diagnosis and 8 weeks after delivery.
Results and perspectives
- Obtain a transcriptionnal signature of preeclampsia
- To identify new mechanism of the disease
- Identification of a specific transcriptom analysis with the comparison after delivery
For long-term, the target is to identify risk patient in order to conduct easily
preventive clinical trials in preeclamsia (primary prevention) and to consider a
specific follow-up for risk patients.
n/a
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