PreDiabetes Clinical Trial
Official title:
Cross-over, Placebo-controlled, Randomized Trial of β-hydroxybutyrate in Prediabetes
The study aims to investigate changes in blood glucose metabolism after administration of a ketone ester drink.
New-onset prediabetes is the most significant risk factor for diabetes. Clinical studies in
healthy human volunteers have demonstrated that ketone esters lower blood glucose levels in
both fasting and fed state.
Participants will visit the COSMOS clinic on two occasions and will be randomly allocated to
receive either the HVMN ketone drink or placebo, in a cross-over design. Blood samples will
be collected sequentially every 30 minutes for up to 150 minutes. Blood samples will be
assayed for glucose and other markers of glucose metabolism.
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