Steroids in Total Knee Arthroplasty

Status Terminated

Clinical Trial Summary

The purpose of this study is to evaluate if the use of two small doses of intravenous (IV) steroids around the time of knee replacement surgery decrease a patient's pain or use of pain medication. The investigators will also determine if the subjects receiving the steroid will have better pain control and better postoperative outcomes after their surgery.

Clinical Trial Description

Adequate pain control after total knee arthroplasty (TKA) is of great importance not only to maximize patient comfort, but also to ensure optimal outcomes after surgery. This study is designed to assess whether the use of two small doses of intravenous (IV) steroids around the time of surgery decrease a patient's pain or use of pain medication. Secondly, the investigators will also determine if the use of these steroids as part of a multimodal pain management strategy leads to improved patient outcomes, including pain, nausea and vomiting, knee function and length of stay in the hospital after surgery. The study will compare the effect of two different doses of IV dexamethasone given preoperatively before TKA, when compared to placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02219581
Study type	Interventional
Source	Emory University
Contact
Status	Terminated
Phase	Phase 4
Start date	October 16, 2014
Completion date	December 1, 2015

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