Clinical Trials Logo

Clinical Trial Summary

With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).


Clinical Trial Description

With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section). The TAP is a space between the muscle layers of the abdominal wall that houses nerves supplying the abdominal skin. The investigators will inject the local anesthetic ropivacaine into this space to freeze these nerves and prevent pain following c-section. The investigators will compare three different doses of ropivacaine (0.5%, 0.25%, 0%) to determine the lowest dose that controls pain with the fewest side effects. Participants in this study will receive 0.5% (Group 1), 0.25% (Group 2), or 0% (Group 3) ropivacaine TAP blocks to control pain after c-section. At 2, 6, 12, 24, and 48 hours after cesarean section visual analog pain scores (VAS) for pain on movement, pain at rest, and pain with cough will be collected along with the time to first postoperative analgesic request, patient satisfaction scores, and patient demographics. The analgesic regimen will be considered effective if it provides lower average visual analog scores for pain with movement. Secondary outcomes will be higher patient satisfaction, better pain control, fewer postoperative analgesic requests, and fewer side effects. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02893423
Study type Interventional
Source Maimonides Medical Center
Contact KALPANA TYAGARAJ, MD
Phone 718-283-1753
Email ktyagaraj@maimonidesmed.org
Status Recruiting
Phase N/A
Start date January 2013
Completion date December 2018

See also
  Status Clinical Trial Phase
Recruiting NCT03181620 - Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation N/A
Recruiting NCT03286543 - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System N/A
Recruiting NCT03663478 - Continuous TQL Block for Elective Cesarean Section Phase 4
Recruiting NCT03612947 - TAP Block in Laparoscopic Cholecystectomy. Phase 2
Recruiting NCT03697278 - Monitoring Postoperative Patient-controlled Analgesia (PCA) N/A
Completed NCT03130049 - Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction N/A
Recruiting NCT03650998 - Transmuscular Quadratus Lumborum Block for Total Laparoscopic Hysterectomy. Phase 4
Not yet recruiting NCT03638960 - Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Rotator Cuff Repair Phase 4
Not yet recruiting NCT03675386 - Reducing Opioid Use for Chronic Pain Patients Following Surgery N/A
Not yet recruiting NCT03639012 - Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy N/A
Not yet recruiting NCT03678168 - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries N/A
Not yet recruiting NCT03064191 - Influence of Intra Canal Medications on Postoperative Flare-up in Endodontic Re-treatment Cases N/A
Completed NCT02866396 - Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Not yet recruiting NCT02762773 - Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss N/A
Completed NCT02824939 - Comparison of Quadratus Lumborum Block With TAP Block for Postoperative Analgesia After Laparoscopic Nephrectomy N/A
Not yet recruiting NCT02724761 - Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion N/A
Recruiting NCT03158376 - Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE). Phase 3
Recruiting NCT02572804 - Comparing Rectus Sheath Catheter to Epidural Post Cystectomy N/A
Recruiting NCT02571153 - Low Doses of Ketamine and Postoperative Quality of Recovery Phase 4
Recruiting NCT00819962 - Perioperative Analgesia Using Ultrasound (US) Guided Transversus Abdominis Plane (TAP) Block Phase 0