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Post-thoracotomy Pain Syndrome clinical trials

View clinical trials related to Post-thoracotomy Pain Syndrome.

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NCT ID: NCT03538340 Recruiting - Clinical trials for Acute Post-thoracotomy Pain

Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.

NCT ID: NCT03051932 Not yet recruiting - Clinical trials for Post-thoracotomy Pain Syndrome

Effects of Intravenous Acetaminophen in Patients Undergoing Thoracoscopic Surgery

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

This is a single-center, randomized, double-blind, placebo-controlled trial. A total of 100 patients, 50 per treatment arm, undergoing minimally invasive thoracic surgery will be randomized 1:1 across 2 treatment arms: Ofiramev® (acetaminophen) injection 1,000 mg (100 mL) plus patient-controlled analgesia (PCA) and 100 mL placebo plus PCA.

NCT ID: NCT02619513 Completed - Clinical trials for Post-thoracotomy Pain Syndrome

Effects of Dexmedetomidine Used in Continuous Thoracic Paravertebral Blocks

Start date: December 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to explore the effectiveness of dexmedetomidine as an adjunctive analgesic, used in ultrasound-guided continuous thoracic paravertebral blocks for Post-thoracotomy Pain Syndrome(PTPS).

NCT ID: NCT01898468 Active, not recruiting - Clinical trials for Post Thoracotomy Pain Syndrome

Post-Thoracotomy Closure Study

Start date: June 2013
Phase: N/A
Study type: Interventional

Post-thoracotomy Pain Syndrome (PTPS) is defined as "pain that recurs or persists along a thoracotomy scar at least 2 months following surgery." PTPS presents a frustrating challenge to patients and healthcare providers alike. PTPS can affect up to 80% of patients undergoing thoracotomies, and results in significant impairment. A proposed mechanism for PTPS is the compression of the intercostal nerves during routine closure. Closure of thoracotomies using intracostal sutures is a novel technique where sutures are passed through holes drilled into the rib; thus, avoiding compression of the nerves. We propose a double-blind, randomized control study involving 90 patients undergoing elective posterolateral thoracotomies. Participants will be randomly assigned to undergo thoracotomy closure with pericostal sutures or intracostal sutures. Our primary outcome will assess the incidence and severity of PTPS at 3, 6, and 12 months after surgery between groups.