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Post Partum Depression clinical trials

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NCT ID: NCT03777046 Not yet recruiting - Clinical trials for Post Partum Depression

Maternal Mental Health

Start date: January 3, 2019
Phase: N/A
Study type: Interventional

Perinatal (around the time of birth) mental health disorders are common difficulties of pregnancy. Perinatal depression is made up of major and minor depressive events during pregnancy and the first 12 months after delivery. It is estimated that 11%-19% of mothers suffer from perinatal depression. However, rates may be significantly higher among some subpopulations. Left untreated, post partum depression (PPD) is linked with several significant negative health impacts on the mother, her infant, and their families. PPD is linked with lower quality maternal-child relationship, and this change in emotional attachment can lead to physiologic changes and poorer cognitive outcomes in the infant. The purpose of this study is to determine the maternal mental health effect of postpartum depression screening and intervention during infants' short term hospitalizations. The study is also aiming to define effects of PPD short term hospitalization interventions on maternal PPD follow up and child health based on well child care (WCC), emergency department (ED) visits, hospital readmissions, and parent's feelings on child's health.

NCT ID: NCT03715218 Completed - Quality of Life Clinical Trials

Impact of Mothers Touch Program to Improve Maternal Health After Birth

Start date: January 21, 2018
Phase: N/A
Study type: Interventional

After the child birth most women experience major health issues such as depression, severe fatigue, back pain, perineal pain, mastitis, urinary or faecal incontinence, sexual problems and relationship problems with partners. That all lead to poorer emotional and mental health and factors contributing isolation, exhaustion and physical health problems. 'Sava Mahina (6-week period) is a traditional practice for postpartum women in India, which include special diet, lifestyle and supportive care. The current multicenter randomized controlled trial (RCT) aims to evaluate outcomes of Indian postpartum care on women.

NCT ID: NCT03703219 Completed - Mood Clinical Trials

Impact of Mothers Touch Program on Women's Psychological Functioning

Start date: April 12, 2018
Study type: Observational

The study investigates the effect of the Mothers Touch program on the psychological well-being of new mothers following 5 weeks of child birth. Mothers Touch Program is designed based on traditional Indian post-partum care given by trained carer in the family. Study was designed as cohort, including a randomised controlled trial.

NCT ID: NCT03665038 Recruiting - Clinical trials for Post Partum Depression

A Study to Assess the Safety and Efficacy of Brexanolone in the Treatment of Adolescent Female Subjects With Postpartum Depression

Start date: May 17, 2018
Phase: Phase 3
Study type: Interventional

This study is a multi-center, double-blind, placebo-controlled study evaluating the efficacy, safety, tolerability, and pharmacokinetics of Brexanolone in the treatment of adolescent female subjects with postpartum depression.

NCT ID: NCT03638687 Recruiting - Bipolar Disorder Clinical Trials

Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers

Start date: May 2014
Study type: Observational

Through a recent cross species translational experiment, researchers have identified a set of epigenetic marks capable of predicting postpartum depression with greater than 85% accuracy. The researchers are looking to identify a group of women from both the general population and those with a history of mood disorders who are at risk for postpartum depression and obtain brain imaging data at a postpartum time period prior to the onset of depressive symptoms and compare it with those obtained during depressive episodes. The researchers will also evaluate the efficacy of postpartum depression biomarker prediction.

NCT ID: NCT03596879 Recruiting - Insomnia Clinical Trials

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

Start date: July 18, 2018
Phase: N/A
Study type: Interventional

The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms. Additionally, the investigators will also determine the effectiveness of digital/internet-based Cognitive Behavioral Therapy for Insomnia (dCBTI) in reducing the risk for PPD.

NCT ID: NCT03438071 Recruiting - Preterm Infants Clinical Trials

Impact of Videoconference Updates in Neonatal Intensive Care Unit on Parental Stress of Preterm Infants (VISIO-NEONAT)

Start date: February 21, 2018
Phase: N/A
Study type: Observational

The aim of the study is to test the effect of daily videoconference updates between parents of preterm newborns and health care providers which also offer them the possibility of seeing their child on the parental stress in a neonatal intensive care unit (NICU).

NCT ID: NCT03417960 Recruiting - Clinical trials for Post Partum Depression

Accelerated iTBS for Post Partum Depression

Start date: January 24, 2018
Phase: N/A
Study type: Interventional

The investigators are studying the feasibility and tolerability of 6x/day intermittent theta burst (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over the course of 3 days for women with post-partum depression. The investigators further hope to characterize the anticipated anti-depressant effect of this treatment paradigm.

NCT ID: NCT03416010 Recruiting - Depression Clinical Trials

Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women

Start date: March 5, 2018
Phase: N/A
Study type: Interventional

The overall purpose of this application is to evaluate the efficacy of an intervention designed to decrease health disparities in pregnant, emotionally distressed, minority women. This randomized controlled trial will test a six session (spaced over 18 weeks) cognitive behavioral skills building (CBSB) prenatal care intervention (specifically designed and based on prior research for pregnant minority women experiencing emotional distress) at two sites (Jacobi Medical Center, New York City and The Ohio State University Total Health and Wellness Clinic,Columbus, Ohio.

NCT ID: NCT03221556 Enrolling by invitation - Clinical trials for Post Partum Depression

Improving Outcomes for Low-Income Mothers With Depression

Start date: February 5, 2018
Phase: N/A
Study type: Interventional

This is a randomized comparative effectiveness trial to improve outcomes among pregnant and post-partum women with symptoms of depression. Both interventions under study will be based in the patient-centered medical home setting at Boston Medical Center - specifically, in prenatal clinic or in the general pediatrics clinic. The study is a type 1 hybrid effectiveness-implementation trial of 230 mothers with clinically significant depressive symptomatology. Of the 230 subjects, half will receive the Engagement-Focused Care Coordination intervention; the other half will receive the Problem Solving Education intervention. Outcomes for mothers will be assessed every 2 months throughout a 12 month follow-up period. This trial is funded by a contract with PCORI, the Patient-Centered Outcomes Research Institute.