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Post-operative Vomiting clinical trials

View clinical trials related to Post-operative Vomiting.

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NCT ID: NCT01732458 Completed - Clinical trials for Post-operative Vomiting

A Study to Evaluate Aprepitant for the Prevention of Post-Operative Nausea and Vomiting in Children (MK-0869-219)

Start date: February 12, 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of aprepitant for the prevention of post-operative nausea and vomiting (PONV) in pediatric participants. Post-operative aprepitant plasma concentrations will be evaluated with a non-compartmental analysis (NCA) at each dose and for each age cohort. Full PK profiles analyzed using population PK modeling and simulation will be described in a separate report.

NCT ID: NCT01725399 Completed - Clinical trials for Post-operative Vomiting

Does First Oral Intake After Emergence Predict the Incidence of Post-operative Vomiting in Children?

XOndansetron
Start date: October 2012
Phase: N/A
Study type: Interventional

Second only to pain, nausea and vomiting are the most uncomfortable complications of surgery and anesthesia. Unfortunately, our best defense against post-operative nausea and vomiting, a medicine called ondansetron (Zofran), is in dire national shortage. Consequently, non-pharmacological methods of prevention and treatment for post-operative nausea and vomiting have increased import. Following emergence from general anesthesia, children often request food and drink. There have been no studies to date that definitively determine the optimal first food or drink choice for these children. This study proposes to randomize children to either water or juice first intake following surgery. The investigators expect to find that children who consume glucose are less likely to vomit than those who first receive water.

NCT ID: NCT01592708 Completed - Clinical trials for Post-operative Nausea

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective surgery.