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Clinical Trial Summary

This study seeks to examine the analgesic efficacy of genicular nerve blocks for pain after total knee replacement.


Clinical Trial Description

Part of the way in which pain is controlled during total knee replacement surgery is through a nerve block. The investigators have developed an effective protocol for pain control after knee replacement, but know that many patients still experience pain around the knee after knee replacement. There are nerves around the knee that carry pain impulses from behind the knee. The investigators believe that placing numbing medicine around these nerves can help with pain in front of the knee after surgery, in addition to the standard nerve block placed for knee replacement surgery. This may result in taking less pain medication by mouth,and having less pain with movement. For this study, before the operation, either a placebo solution or the local anesthetic bupivacaine (a numbing solution) will be placed at three sites around the knee where these nerves reside. The investigators will evaluate how participants feel in recovery after surgery, during the stay in the hospital, and call at home one week after surgery. Knowing if numbing these nerves helps with pain after surgery will help us further refine our postoperative care plan for patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03706313
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Phase 4
Start date January 15, 2019
Completion date October 22, 2019

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