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Effects of Ondansetron Dose and Timing on Post-operative Nausea and Vomiting

Post-operative Nausea and Vomiting Clinical Trial

Official title:
Effects of Ondansetron Dose and Timing on Rates of Post-operative Nausea and Vomiting

Clinical Trial Summary

The aim is to evaluate the effectiveness of three different regimens of prophylactic ondansetron on the incidence and severity of post-operative nausea and vomiting.

Clinical Trial Description

Patients will be randomize to one of three arms: 4mg ondansetron pre-emergence, 8 mg ondansetron pre-emergence, or 4mg ondansetron pre-incision followed by 4mg ondansetron pre-emergence. Primary outcome will be incidence of PONV in the PACU prior to discharge. ;

Study Design

Related Conditions & MeSH terms

  • Nausea
  • Post-operative Nausea and Vomiting
  • Postoperative Nausea and Vomiting
  • Vomiting
Clinical Trial Details
NCT number NCT03297021
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact
Status Completed
Phase Phase 4
Start date October 23, 2017
Completion date April 5, 2019
View Details
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