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Post-Operative Nausea and Vomiting (PONV) clinical trials

View clinical trials related to Post-Operative Nausea and Vomiting (PONV).

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NCT ID: NCT02384187 Completed - Adenotonsillectomy Clinical Trials

Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The frequent incidence of postoperative vomiting and severe pain in children undergoing adenotonsillectomy, may delay postoperative oral intake and increase the risk of dehydration. Postoperative nausea and vomiting (PONV) is of multi-factorial origin in this group of patients, with a reported incidence ranging from 23% to 73%. There is growing evidence that the perioperative administration of gabapentinin in adults is beneficial for preoperative anxiolysis, postoperative analgesia, reduction of postoperative nausea and vomiting, and delirium. Only few studies in literature explored the analgesic effects of preoperative gabapentin as premedication in pediatric population. However, the antiemetic effect of gabapentin in pediatric patients was not systematically investigated before.

NCT ID: NCT01290133 Completed - Clinical trials for Post-Operative Nausea and Vomiting (PONV)

Single Dose Safety Study for Compound to Treat Post-Operative Nausea and Vomiting (PONV)

Start date: May 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to describe the safety and tolerability and pharmacokinetics of a single intravenous administration of the new, Sulfobutyl Ether-7-Beta-Cyclodextrin (Captisolâ„¢) based, formulation in Healthy Adult Subjects.