Post-operative Hemorrhage Clinical Trial
Official title:
Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy
Tonsillectomy (removal of the tonsils) is a very common surgery in children. Bleeding after
tonsillectomy is one of the risks of this surgery and can be more dangerous in children
since they have less blood volume than adults. In order to improve recovery after
tonsillectomy, steroids (medication that is a strong anti-inflammatory) are often given
during the surgery. Recently, a study showed steroids given at the time of tonsillectomy
increase the risk of bleeding significantly over children who did not receive steroids. This
finding has raised concerns in the Ear, Nose, and Throat (ENT) community since most ENT's
use steroids during tonsillectomy in children. The investigators look to explore this
question further.
To answer the question of whether perioperative steroid administration significantly affects
the rate of post-tonsillectomy bleeding, the investigators propose to test the following
hypotheses in a prospective, randomized, blinded placebo-controlled trial: dexamethasone
does not cause an increase in post-operative bleeding rate in tonsillectomy.
Not desired ;
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment