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Post Operative Cardiac Surgery clinical trials

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NCT ID: NCT02056977 Recruiting - ARDS Clinical Trials

PEEP Levels Selected by PEEP Titration and PEEP Levels Routinely Used in Post-operative Cardiac Patients With Hypoxemic Respiratory Failure

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to: - Compare PEEP level selected by individualized PEEP titration by electrical impedance tomography and PEEP level routinely used in post-operative cardiac patients with Hypoxemic Respiratory Failure; - Evaluate the agreement between the results of a rapid titration (total procedure duration = 5 min) versus an already validated slow titration (total procedure duration = 40 min) of the same patient, sequentially. Specifically, degree of collapse and degree of distention in each PEEP level, estimated by EIT; - Compare hemodynamics during the two maneuvers of PEEP titration; - Evaluate the efficacy of the selected PEEP (minimum PEEP preventing lung collapse less than 5%) to maintain stable levels of the following variables: arterial oxygenation, respiratory system compliance, and degree of collapse by EIT; - Compare these results (evolution of the three variables, along 4 hours) with the control strategy (default strategy currently used in the institution) group.