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Clinical Trial Summary

The aim of this Register Trial is to systematically study the epidemiology, risk factors, liver function as well prognosis of patients with vascular liver diseases. Furthermore, important clinical parameters will be assessed in order to evaluate patients' coagulation status and in order to develop new biomarkers derived from blood, urine, stool or ascites of patients as well as histological samples from the upper / lower GI-tract or the liver in order to better understand the natural history of vascular liver diseases.


Clinical Trial Description

We will include patients with vascular liver diseases, including - portal vein thrombosis (PVT) - Budd-Chiari Syndrome (BCS) - Heredetary Hemorrhagic Teleangiectasia (HHT, or Osler-Rendu Disease) - Noncirrhotic-portal hypertension (NCPH) and Porto-sinusoidal vascular disorder - Cirrhosis cardiaque if the fulfill inclusion/exclusion criteria and provide written informed consent. Participation in the biobank is optional for the patients. In particular, we will study the natural course of the patients in regard to hepatic decompensation (ascites, variceal bleeding, hepatic encephalopathy), need for intensified treatment (TIPS, ICU, liver transplantation) and survival. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03541057
Study type Observational [Patient Registry]
Source Medical University of Vienna
Contact Thomas Reiberger, MD
Phone 0043140400
Email thomas.reiberger@meduniwien.ac.at
Status Recruiting
Phase
Start date December 12, 2017
Completion date December 2024

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