Pneumoperitoneum Clinical Trial
Official title:
Insufflation With Carbon Dioxide Reduces Pneumoperitoneum After Percutaneous Endoscopic Gastrostomy (PEG): A Randomized Controlled Trial
The investigators hypothesize that using carbon dioxide for PEG placement versus using room air will decrease post-procedure pneumoperitoneum as well as improve post-procedure bloating/pain, and waist circumference.
Background and study aims: Pneumoperitoneum following PEG placement has been reported in up
to 60% of cases, and while usually benign and self-limited, it can lead to evaluation for
suspected perforation. This study was designed to determine whether using CO2 compared to
ambient air for insufflation during PEG reduces post-procedure pneumoperitoneum.
Patients and Methods: Prospective, double blind, randomized trial of 35 consecutive patients
undergoing PEG at a single academic medical center. Patients were randomized to insufflation
with CO2 or ambient air. Primary outcome was pneumoperitoneum determined by left-lateral
decubitus abdominal x-rays 30 min after PEG placement. Secondary endpoints included
abdominal distention, pain, and bloating.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT06075836 -
AI Assisted Detection of Chest X-Rays
|
||
| Completed |
NCT03608436 -
The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Early Quality of Recovery
|
Phase 4 | |
| Completed |
NCT03572413 -
The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis.
|
Phase 4 | |
| Completed |
NCT04146090 -
Low-pressure vs Standard-pressure in Laparoscopic Cholecystectomy
|
N/A | |
| Completed |
NCT02853591 -
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
|
N/A | |
| Completed |
NCT03576118 -
Moderate vs Deep Neuromuscular Block on Biotrauma During Laparoscopy
|
N/A | |
| Completed |
NCT02079337 -
Validation of Subjective Rating Scales Used to Assess Surgical Conditions in Abdominal Surgery
|
Phase 4 | |
| Completed |
NCT01512511 -
Comparing Nitrous Oxide and Carbon Dioxide for Laparoscopic Cholecystectomy
|
N/A | |
| Not yet recruiting |
NCT06116383 -
Evaluation of Renal Perfusion With NIRS in Laparoscopic Surgery
|
||
| Withdrawn |
NCT03933254 -
Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies
|
||
| Recruiting |
NCT03069586 -
Effect Low Pressure Pneumoperitoneum and Pulmonary Recruitment on Postoperative Pain
|
N/A | |
| Recruiting |
NCT01867814 -
Arterial and Plethysmographic Waveforms Variables as Predictors of Hemodynamic Response to Pneumoperitoneum
|
N/A | |
| Terminated |
NCT01854307 -
The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements
|
N/A | |
| Recruiting |
NCT06447545 -
Comparison Between Low Pressure Pneumoperitoneum With High Pressure Pneumoperitoneum in Post-operative Pain, Shoulder Tip Pain and Common Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy
|
N/A | |
| Completed |
NCT05992636 -
Different Insufflation Flows and Effects on Cerebral Oxygenation in Laparoscopic Cholecystectomy
|
||
| Completed |
NCT03957837 -
Optical Nerve Sheath Changes During Head Down Laparoscopy
|
||
| Recruiting |
NCT06319053 -
The Turbine-based Insufflator Safety and Feasibility Study
|
N/A | |
| Completed |
NCT04125173 -
Effect of Lower Pneumoperitoneum Pressure During Laparoscopic and Robotic Hysterectomy
|
N/A | |
| Not yet recruiting |
NCT02690688 -
Intra-abdominal Pressure and Dynamic Preload Variables
|
N/A | |
| Completed |
NCT05238506 -
Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
|
Phase 4 |