Clinical Trials Logo
  1. Home
  2. Platelet Dysfunction
  3. NCT04554901

The Effect of Cocoa on Platelet Function Profiles in Patients — ECLAIR  

Platelet Dysfunction Clinical Trial

Official title:
The Effect of Cocoa on Platelet Function Profiles in Patients With Stable Coronary Artery Disease in Trinidad and Tobago: The ECLAIR Study

Clinical Trial Summary

The effects of chocolate on cardiovascular health are still a matter of debate. It can potentially favor cardiovascular health through the antioxidative effects of cocoa ingredients, such as polyphenols (present in dark but not white chocolate).

Clinical Trial Description

Epidemiologic studies have shown inverse associations between dietary polyphenols (present in dark chocolate and cocoa) and mortality from coronary heart disease. However, the basis for this protective association is uncertain. Food polyphenols such as in cocoa reportedly have antioxidant properties and decrease platelet function in vitro. The goal of the present study was to investigate whether the beneficial antioxidant effect of polyphenol-rich cocoa can induce an improvement of endothelial and platelet function in patients with stable coronary artery disease with known platelet hyperreactivity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04554901
Study type Interventional
Source The University of The West Indies
Contact
Status Completed
Phase N/A
Start date September 1, 2020
Completion date June 30, 2022
View Details
See also
  Status Clinical Trial Phase
Completed NCT03621020 - Clinical Performance Evaluation of T-TAS 01 PL Chip
Completed NCT03667066 - clOpidogrel "resIstaNce" in a Selected Population of Patients at a Tertiary Cardiovascular Center in Trinidad
Recruiting NCT05588011 - Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmonary Bypass N/A
Completed NCT01454427 - Influence of Anesthesia Drugs on Impedance Aggregometry N/A
Completed NCT03188705 - CES1 Carriers in the PAPI Study Phase 4
Recruiting NCT03583229 - Coronary Artery Disease After Heart Transplantation N/A
Recruiting NCT05730114 - Monitoring Antiplatelet Drugs in Cardiac Arrest Patients
Completed NCT03182946 - Correcting Platelet Dysfunction After Traumatic Brain Injury
Completed NCT05033236 - Platelets and Complement Activation in Coronary Artery Bypass Graft Surgery (CABG)
Recruiting NCT04419948 - Oleocanthal Rich Olive Oil Acute Effects on Hyperglycemia and Platelet Activation in T2DM N/A
Completed NCT04400760 - The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts. Phase 2/Phase 3
Completed NCT03458351 - RIPC and Platelet Activation on Platelet Activation During Cardiopulmonary Bypass N/A
Completed NCT02368730 - Documentation of the Efficacy of Desmopressin Within the Context of Surgical Procedures N/A
Not yet recruiting NCT04876573 - Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19 Phase 2
Completed NCT04734028 - PTRG-DES Consortium
Completed NCT01382134 - Effect of Aspirin, Hemodilution and Desmopressin on Platelet Dysfunction N/A
Completed NCT03028064 - Point of Care Testing of Platelet Function in Patients With Acute Upper Gastrointestinal Bleeding
Completed NCT05237492 - The Influence of Tramadol on Platelet Function Phase 4
Completed NCT01957345 - Evaluation of a New Approach of the Diagnosis of Constitutional Functional Disorders of Platelets N/A
Completed NCT03049566 - Low-dose Acetylsalicylic Acid Before Non-cardiac Surgery N/A