Peripheral Neuropathy Clinical Trial
Official title:
Electrophysiological Evaluation of Motor Dysfunction in Liver Cirrhotic Patients
cross sectional observational study, aimed to assess the electrophysiological function of the motor units in liver cirrhotic patients.
Liver cirrhosis is a global health problem which could be associated with several
neurological manifestations. The associated peripheral neuropathy could be assessed by
conventional nerve conduction studies.
Objective: The study aims at early detection of peripheral neuropathy among patients of liver
cirrhosis by conventional nerve conduction studies and quantitative EMG methods. In addition,
the study aims at finding out correlation between peripheral neuropathy and severity of the
liver cirrhosis.
Methods: This a cross-sectional study conducted on fifty-six liver cirrhotic patients, that
had been recruited from the Endemic medicine department/outpatient clinics and their
age-gender matched sixty-one healthy controls. The recruited patients were clinically
assessed .Both conventional nerve conduction studies and quantitative EMG techniques in the
form of MUNE calculation, using modified spike -triggered technique and IPA ratio evaluation
were performed for the allocated cirrhotic patients.
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