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L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients With Breast Cancer

Peripheral Neuropathy Clinical Trial

Official title:
L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients With Breast Cancer

Clinical Trial Summary

The purpose of the study is to determine whether daily, high-dose administration of l-glutamine can reduce numbness and tingling caused by a taxane chemotherapy in patients with breast cancer.

Clinical Trial Description

L-glutamine has previously been shown to help reduce the incidence of numbness and tingling in patients with breast cancer who are receiving taxane chemotherapies. However, no study to date looks at the effect of l-glutamine given after this numbness and tingling (called 'perihperhal neuropathy') has already occurred. We hypothesize that administration of this amino acid in l-glutamine naïve patients will result in a measureable reduction of their taxane-induced neuropathy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02215083
Study type Interventional
Source Eastern Regional Medical Center
Contact
Status Withdrawn
Phase Phase 1
Start date August 2014
Completion date April 2015
View Details
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