Periodontal Diseases Clinical Trial
Official title:
A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases (A Randomized, Double-blind Clinical Trials)
Aim: clinical effectiveness of 0.05% cetylpyridinium chloride mouth rinse in patients with
gingivitis as compared to non-alcoholic chlorhexidine mouth wash.
Methods & Material: Twenty-four subjects, without systemic diseases, with plaque-induced
gingivitis will be selected for this study. The patients were treated with scaling and root
planing at the baseline; Oral hygiene instructions were given that included brushing twice-
daily, The volunteers brushed their teeth with the Bass brushing technique for at least 2
minutes, these patients were randomly ,equally divided into two groups, Group A: perform
daily mouthwashes twice a day with the solution containing 10 ml of 0.05 cetyl pyridinium,
(Vi-one, Rojin, Cosmetic-Lab, Kurdistan -Iran), Group B: use daily mouthwashes twice a day
with 10ml of the chlorhexidine(Kin Laboratories, Spain), On day 0,7,15 and day 21 of each
phase the Plaque Index (PI), Pocket depth(PD), Stain Index(SI) and Bleeding Index (BI) of
each volunteer were measured.
In this study, 34 patients referred to periodontics Department that no serious systemic disease in terms of periodontitis and disease Gingivitis (ie pockets of periodontal tissue to a depth of less than or equal to 4 mm without CAL in the jaw down or up) the following explanation necessary for the procedure tastings consent, the index of oral hygiene (plaque index) index # Turesky, pocket depth and to control the inflammatory condition * bleeding index bleeding during the probe based on Carter and Barnes (if any bleeding number 1 and its absence 0) and attachment loss were evaluated areas. The amount of pigment (Stain) after of using mouthwash based on S.I (Stain Index) was evaluated . ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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