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Adenosine Contrast CorrELations in Evaluating RevAscularizaTION — ACCELERATION  

Percutaneous Coronary Intervention Clinical Trial

Official title:
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION

Clinical Trial Summary

The purpose of this study is to compare FFR measurements done with adenosine to FFR measurements done with contrast, where the contrast is injected using the ACIST CVi automated contrast injector. The ACCELERATION study will support a safer approach to FFR for patients by potentially reducing toxic drug exposure (adenosine). The 2 main objectives of the study are: 1. Perform a methods comparison between cFFR and the reference standard aFFR, where cFFR is performed using an automated injector with a standardized volume and rate of delivery of contrast with known osmolality. 2. Evaluate the association between final post-PCI FFR and long-term clinical outcomes. The long-term clinical outcomes will include TVR and composite MACE (death, MI, and TVR) at 30 days and 1 year.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Percutaneous Coronary Intervention
Clinical Trial Details
NCT number NCT03557385
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Phase 4
Start date January 17, 2019
Completion date April 4, 2023
View Details
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