Paracetamol Versus Ibuprofen for PDA Closure

Status Active, not recruiting

Clinical Trial Summary

Comparison between the safety and efficacy of oral paracetamol and oral ibuprofen in treatment of Patent Ductus Arteriosus (PDA) in premature infants

Clinical Trial Description

A pilot study through which we have studied efficacy and safety of oral paracetamol and oral ibuprofen in treatment of hemodyamically significant pda in preterm neonates. 30 preterm neonates were included in the study 15 per each group. echo was done in the beginning and during treatment with both drugs to follow up the closure of the duct.

Ibuprofen was given as 10 mg/kg/dose in the 1st day followed by 5 mg/kg/dose in the 2nd and 3rd days with follow up echo was done after finishing the course paracetamol was given as 15 mglkg/6 hrs for three days with follow up echo to check the ductal closure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03265782
Study type	Interventional
Source	Ain Shams University
Contact
Status	Active, not recruiting
Phase	Phase 4
Start date	June 2015
Completion date	January 2018

View Details

See also
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