Parkinson's Disease Clinical Trial
Official title:
Efficacy and Safety Study:The Influence of Repetitive Transcranial Stimulation (r-TMS) Treatment on Motor and Cognitive Measurements in Patients With Parkinson's Disease
The purpose of this study is to test the effects of deep rTMS using the novel H-coil on the motor, affective and cognitive deficits in patients with Parkinson's disease (PD) and to establish its safety in this population.
Study rational:We anticipate that reaching deeper brain layers and larger volume of
activation with the novel H-coil may induce significantly better therapeutic effects in
patients with PD and will pave the way for establishing a novel and effective treatment for
this disorder.
Design:A prospective, double blind sham-controled study. No. of centers:1 One: Tel-Hashomer
Medical Center, affiliated to Sackler school of Medicine, Tel -Aviv University, Israel.
Study Population:Forty patients with idiopathic PD, Hoehn and Yahr stages II to IV, on
stable antiparkinsonian therapy, with partial response.
Study Duration:Two years
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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