Clinical Trials Logo
NCT number NCT03495193
Study type Interventional
Source University of Alabama at Birmingham
Contact Amy Amara, MD, PhD
Phone 205-934-0683
Status Recruiting
Phase N/A
Start date May 18, 2017
Completion date May 2020

Clinical Trial Summary

The goal of this research is to identify an intervention that will improve cognition and sleep in persons with PD.

Clinical Trial Description

Persons with Parkinson's disease (PD) often experience non-motor symptoms such as cognitive dysfunction and sleep problems. These symptoms can be more disabling than the motor symptoms of PD. Medications are often not effective for treating these non-motor symptoms or can have unwanted side effects. Non- medication treatments such as exercise are known to improve the motor symptoms of PD, but the effect of exercise on cognition and sleep has not been fully explored. This study investigates the impact of 16 weeks of supervised exercise, 3 times per week, compared to no-exercise over the same duration, on cognition and sleep dysfunction. Participants will be evaluated with cognitive tests and sleep studies before and after 16-weeks to determine the impact of this exercise intervention. The goal of this research is to identify an intervention that will improve cognition and sleep in persons with PD.

Study Design

Related Conditions & MeSH terms

See also
  Status Clinical Trial Phase
Recruiting NCT03272230 - Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System N/A
Recruiting NCT03497884 - Individualized Precise Localization of rTMS on Primary Motor Area N/A
Recruiting NCT03257046 - Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ITI-214 in Parkinson's Disease Phase 1/Phase 2
Recruiting NCT03295786 - Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease Phase 1/Phase 2
Completed NCT03103399 - Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon Phase 2
Suspended NCT03104725 - Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease? N/A
Recruiting NCT03014050 - Bio Electro Stimulation Therapy for Parkinson's Disease N/A
Recruiting NCT02869945 - Compensation Mechanisms in Parkinson's Disease N/A
Recruiting NCT03045211 - Post-Physical Therapy Extension of In-Home Dynamic Standing Table Use in Parkinson Disease N/A
Recruiting NCT03192046 - Bracing for Walking in Parkinson's Disease N/A
Recruiting NCT02823158 - Bilateral Pallidal Stimulation in Patients With Advanced Parkinson's Disease-LATESTIM N/A
Recruiting NCT02601586 - Effects of PR Oxycodone and of Levodopa, vs Placebo, on Central Neuropathic Pain in Parkinson's Disease Phase 2/Phase 3
Recruiting NCT02897063 - Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Phase 1
Recruiting NCT03143374 - Positron Emission Tomography (PET) Imaging of Tau Pathology in Neurodegenerative Disease N/A
Not yet recruiting NCT02855021 - Prediction of Dementia in Parkinson's Disease by Measuring Cerebral Metabolism With PET Scan N/A
Recruiting NCT02718560 - Handwriting Rehabilitation in Parkinson Disease N/A
Recruiting NCT03288909 - Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease N/A
Completed NCT02547506 - Comparison of Cardiorespiratory Fitness Among Regular Exercisers With and Without Parkinson Disease and Across Different Modes of Group Exercise N/A
Completed NCT02763891 - Effect of Body Suspension and Tilting Exercises in Parkinson's Disease N/A
Recruiting NCT02205216 - Can tDCS Enhance Efficacy of Rehabilitative Intervention for Freezing of Gait in Parkinson's Disease? N/A