Parkinson Disease Clinical Trial
Official title:
Can Transcranial Direct Stimulation Enhance the Efficacy of a Rehabilitative Intervention for the Treatment of Freezing of Gait in Parkinson's Disease? A Double Blind Randomized Controlled Study
Freezing of gait in Parkinson's disease (PD) is a major cause of disability and falls and
responds often incompletely to conventional therapy. The pathogenesis remains largely
unknown and therapeutic alternatives are needed. Rehabilitative interventions that consist
of learning cognitive strategies with sensory cueing to prevent and to overcome FOG
represent the most efficacious intervention, but difficulties in learning and execution of
these cognitive strategies are the main cause of failure. Transcranial direct current
stimulation (tDCS) enhances motor task learning and execution in patients with PD and might
enhance the efficacy of rehabilitative interventions.
This study intends to address the following question whether tDCS can enhance the efficacy
of rehabilitative interventions in the treatment of freezing of gait in Parkinson's disease?
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor)
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