Pancreatic Cancer Clinical Trial
Official title:
Study of the Kinetics of Microparticles Under Chemotherapy in Patients With Gastric or Pancreatic Cancer
Microparticles have recently emerged as a thrombotic risk marker with a potential role in
determining which patients are at greatest risk for developing thrombosis. Available data
show an increase in the level of microparticles in cancer patients who are undergoing
chemotherapy for solid tumors with a possible link to their thrombogenic state.
Our study focuses on the kinetics of microparticles under chemotherapy in patients with
pancreatic or gastric cancer by serial measurements of microparticles procoagulant activity.
Detailed Description:
The impact of chemotherapy on microparticles expression will be assessed by measuring their
procoagulant activity on blood samples taken during the course of chemotherapy. The
thrombotic risk will be evaluated by the score of Khorana in parallel. Microparticles
expression in patients with thrombosis will be compared to that in other patients.
n/a
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