Efficacy of Injectable Vitamin C on Accelerating Canine Movement: A Clinical Study

Palatally Impacted Canines Clinical Trial

— mesotherapy  

Official title:

Evaluation of the Effect of Local Injected Vitamin C on Accelerating the Orthodontic Movement of Maxillary Canine Impaction: A Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03260829
• Other study ID #: oral and dental medicine
• Secondary ID: no conflict of i
• Status: Completed
• Phase: N/A
• First received: January 11, 2017
• Last updated: August 25, 2017
• Start date: January 2014
• Est. completion date: February 2015

Study information

• Verified date: August 2017
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

efficacy of the injectable vitamin C to reduce the time of canine traction

Description:

Objective. The purpose of this study is to investigate the role and efficiency of the locally injected vitamin C in the enhancement of the palatally impacted canine movement.

Design. Twelve adult patients with unilateral palatally impacted canines were included in this study. The enrolled patients were randomly allocated into the study groups; control group; orthodontic traction and he test group: orthodontic traction enhanced by intraepidermic vitamin C injection. The study duration was 12 months.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: February 2015
• Est. primary completion date: January 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 15 Years to 40 Years

Eligibility

Inclusion Criteria:

• medically free

• patient with good to fair oral hygiene (gingivitis may be included)

• both sexes were included

• unilateral palatally positioned permenant canines

• absence of previous orthodontic treatment

• absence of supernumerary teeth, odontoms, cysts, traumatic injuries

• the a angle within grade II to III

Exclusion Criteria:

• systemic diseases especially diabetes and bone diseases

• pregnant and lactating mothers

• Local causes (smoking, mouth breathing, local trauma and periodontitis).

Related Conditions & MeSH terms

• Palatally Impacted Canines
• Tooth, Impacted

Intervention

Drug:
• vitamin C
25 IU of vitamin C injected intraepidermally for 6-8 visits till eruption achieved

Locations

Country	Name	City	State
Egypt	Faculty of Oral and Dental Medicine	Gizah	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Makar AB, McMartin KE, Palese M, Tephly TR. Formate assay in body fluids: application in methanol poisoning. Biochem Med. 1975 Jun;13(2):117-26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	rate of tooth movement	the achieved movement in millimeters in one year	12 months
Secondary	level of alveolar bone	the level of the interproximal and facial alveolar bone after orthodontic treatment with or without injection	12 months