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Painful Diabetic Peripheral Neuropathy clinical trials

View clinical trials related to Painful Diabetic Peripheral Neuropathy.

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NCT ID: NCT03172598 Recruiting - Clinical trials for Painful Diabetic Peripheral Neuropathy

Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Start date: July 25, 2017
Phase: Phase 2
Study type: Interventional

A Study to Investigate the Safety, Tolerability and Efficacy of Multiple Doses of MT-8554 in Subjects with Painful Diabetic Peripheral Neuropathy

NCT ID: NCT01726413 Completed - Clinical trials for Painful Diabetic Peripheral Neuropathy

A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).

Start date: November 2012
Phase: Phase 2
Study type: Interventional

Diabetic peripheral neuropathy (DPN) represents a diffuse symmetric and length-dependent injury to peripheral nerves that has major implications on quality of life (QOL), morbidity, and costs from a public health perspective. Painful diabetic neuropathy affects approximately 16% of patients with diabetes. Pharmacological agents used in the management of painful DPN mainly include tricyclic antidepressants, selective serotonin and norepinephrine reuptake inhibitors, opioid, and anti epileptic drugs. The available treatment options do not give total relief, are not effective in all patients, and only about one-third of patients may achieve more than 50% pain relief. Hence newer therapies are required for the treatment of DPN. The primary outcome measures will be the change from baseline to end of treatment in the mean 24-hour average pain intensity.

NCT ID: NCT01455415 Completed - Clinical trials for Painful Diabetic Peripheral Neuropathy

Effect Of Pregabalin Treatment In Patients With Diabetic Nerve Pain Who Currently Use A Non-Steroid Anti-Inflammatory Drug (NSAID) For Another Pain

Start date: December 2011
Phase: Phase 3
Study type: Interventional

This study is to test the effectiveness of pregabalin in treating nerve pain caused by diabetes. The suitable subjects will be patients who also use an non-steroid anti-inflammatory drug for another pain which is not related to the diabetic nerve pain.

NCT ID: NCT01280747 Terminated - Fibromyalgia Clinical Trials

Examination of Pregabalin Access for Treatment of Indicated Pain Disorders: the ExPAND Study

Start date: January 2011
Phase: Phase 4
Study type: Observational

The investigators hypothesize that fibromyalgia (FM) and painful diabetic peripheral neuropathy (pDPN) patients with access restrictions on pregabalin will lead to higher healthcare resource use and cost compared to patients without such restrictions on pregabalin in a naturalistic setting. The randomization will occur at the physician level and not the patient level.