The Effects of Non Harmonic and White Noise on Human Pain Sensitivity: a Study of Healthy Volunteers

Pain Clinical Trial

Official title:

The Effects of Non Harmonic and White Noise on Human Pain Sensitivity: a Study of Healthy Volunteers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06165757
• Other study ID #: Noise and pain sensitivit
• Status: Completed
• Phase: N/A
• Start date: October 10, 2023
• Est. completion date: January 20, 2024

Study information

• Verified date: October 2023
• Source: The Second Affiliated Hospital of Chongqing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Study the effects of 60dB and 80dB white noise, 50-70dB and 70-90dB non harmonic tones on the basic pain threshold of subjects, including the threshold and tolerance of electrical stimulation pain,the threshold and tolerance of cold pain stimulation, and the threshold and tolerance of tenderness stimulation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: January 20, 2024
• Est. primary completion date: January 20, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Between the ages of 18 and 35, regardless of gender

• No serious chronic diseases

• There is no self-reported history of chronic opioid drug use or neuropathy

Exclusion Criteria:

• A history of alcohol or drug abuse

• Pregnant or lactating

• Severe cardiovascular, kidney, or liver diseases

Related Conditions & MeSH terms

• Hypersensitivity
• Pain

Intervention

Behavioral:
• noise stimulation
Apply non harmonic and white noise sound stimuli to the subjects, and then measure the threshold and tolerance values of pressure pain, cold pain, and electrical pain.

Locations

Country	Name	City	State
China	Department of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University	Chongqing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
The Second Affiliated Hospital of Chongqing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mechanical pain sensitivity	Each participant was measured using the pressure pain threshold and tolerance (tested by a pressure meter), which lower value present higher pain sensitivity	from the study beginning to 30 min after the procedure
Primary	cold pain sensitivity	Each participant was measured using the cold pain threshold and tolerance (tested by immersion the hand in 4? water), which lower value present higher pain sensitivity	from the study beginning to 30 min after the procedure
Primary	electrical pain sensitivity	Each participant was measured using the cold pain threshold and tolerance (tested by a electrical stimulator), which lower value present higher pain sensitivity	from the study beginning to 30 min after the procedure