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NCT number NCT03393546
Study type Interventional
Source Johns Hopkins University
Contact
Status Not yet recruiting
Phase N/A
Start date February 1, 2018
Completion date December 30, 2018

Clinical Trial Summary

Pain is considered as one of the most important causal factors of behavioral and psychological symptoms in patients Alzheimer's disease and related disorders (ADRD). The investigators plan to examine the effectiveness of pain relief, pain sensory change (measured by quantitative sensory testing) and immune biomarkers change (measured by serum biomarkers) after the auricular point acupressure (APA). A waitlist and education control will be used to examine the feasibility of a 4-week APA intervention. The investigators will also explore potential analgesic pathways and underpinnings of APA on pain relief.


Clinical Trial Description

A waitlist and education control pilot study will be conducted to examine the feasibility of a 4-week APA intervention. This study will be conducted in two phases. In Phase 1, following the baseline assessment (1st home visit), participants will wait one month and will be randomized to an APA or education control group (to control time and attention). For the education control, each participant will be given 3 Alzheimer's Association publications (i.e., Basics of AD; Take Care of Yourself; and Behaviors). Both groups will have 1st office visit at pre-intervention, followed by three home visits weekly, 2nd office visit (post-intervention). After post-intervention assessment, the education control participants will cross over to the APA protocol. Participants at both groups will have three monthly follow-up (3 home visits) after the completion of APA. In Phase 2, all participants will be reassessed every three months for 6 months (2 follow-up phone surveys).


Study Design


Related Conditions & MeSH terms


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