Pain Clinical Trial
Official title:
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
The study is a controlled, double blind, prospective, randomized and performed at
Sahlgrenska University Hospital in Goteborg, Sweden. The injectant mixture consists of 300
mg ropivacaine mixed with 30 mg ketorolac and 0.5 mg epinephrine. Total volume of the
solution is 156 ml. The normal saline injection is used in the control group in the same
manner as in the LIA group. The parameters which would be evaluated are consumption of
morphine, pain intensity and side effects.
The primary objective is to evaluate whether local infiltration analgesia (LIA) into the
operating field will reduce morphine consumption during the first 24 postoperative hours in
patients undergoing abdominal hysterectomy (AH).
Secondary end-points are pain intensity, incidence of nausea and vomiting, sedation
intensity.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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