Ovarian Cancer Clinical Trial
Official title:
A Phase II Study of Efficacy and Safety of Paclitaxel and Cisplatin Every 2 Weeks as the First-line Treatment of Patients With Ovarian Cancer Stage Ic-IV.
RATIONALE: Drugs used in chemotherapy, such as paclitaxel and cisplatin, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.
PURPOSE: This phase II trial is studying the side effects of giving paclitaxel together with
cisplatin as first-line therapy and to see how well it works in treating patients with stage
I, stage II, stage III, or stage IV ovarian epithelial cancer.
OBJECTIVES:
- To investigate the efficacy and safety of paclitaxel and cisplatin as first-line
chemotherapy in patients with stage IC-IV ovarian epithelial cancer.
OUTLINE: This is a multicenter study.
Patients receive paclitaxel IV and cisplatin IV once every 2 weeks. Treatment repeats every
2 weeks for 9 courses in the absence of disease progression or unacceptable toxicity.
;
Masking: Open Label, Primary Purpose: Treatment
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