NHF in Acute Hypercapnic Acute Exacerbation of COPD

Safety of NHF in Acute Hypercapnic AECOPD Clinical Trial

Official title:

NHF in Acute Hypercapnic Acute Exacerbation of COPD

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03523481
• Other study ID #: 2
• Status: Completed
• Start date: May 15, 2018
• Est. completion date: May 30, 2018

Study information

• Verified date: June 2018
• Source: University of Leipzig
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Patients with AECOPD and NIV failure and in absence will be treated with NHF device. Inclusion criteria are pH < 7,38 and pCO2 > 45 mm Hg. Patients were treated if pH >7,38 or refusal of therapy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: May 30, 2018
• Est. primary completion date: May 30, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• pH < 7,38

• hypercapnic AECOPD

Exclusion Criteria:

• Need of intubation

Related Conditions & MeSH terms

• Hypercapnia
• Safety of NHF in Acute Hypercapnic AECOPD

Locations

Country	Name	City	State
Germany	University of Leipzig	Leipzig

Sponsors (1)

Lead Sponsor	Collaborator
Jens Bräunlich, MD

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pH	Increase in pH	up to 24 hours
Secondary	pCO2	Decrease in pCO2	up to 24 hours