Postoperative Nausea and Vomiting Clinical Trial
Official title:
Gabapentin Premedication to Reduce Postoperative Nausea and Vomiting in Surgical Patient Receiving Spinal Morphine
The intrathecal administration of morphine is gaining popularity. It is easy to do and can reduce the pain after surgery up to 24 hours. However, it causes postoperative nausea and vomiting more than other methods providing postoperative analgesia. Patients suffering from these side effects have to spend a longer period of time recovering in the hospital with high cost of medical treatment.
Objective: to study the efficacy of oral administrating of gabapentin 600 mg before surgery
to reduce the postoperative nausea and vomiting in patients receiving intrathecal morphine.
Methods: Eighty patients undergoing orthopedic surgery and receiving intrathecal morphine
will be randomized into 2 groups. The first group will receive oral gabapentin 600 mg and
the second group will receive a placebo tablet. Both groups will receive a standard
prophylactic medication for postoperative nausea and vomiting. The degrees of nausea and
vomiting in both groups will be assessed over 24 hours postoperatively.
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