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Clinical Trial Summary

This study consists of two research phases: Phase Ib (includes dose escalation phase and efficacy extension phase): To explore the safety, tolerability and initial efficacy of SHR-A1904 in the treatment of CLDN18.2-positive advanced solid tumors, and to determine the recommended dose and recommended population for the Phase III combination study. Phase III: A randomized, double-blind, multicenter clinical study of SHR-1904 combined with chemotherapy and immunotherapy Versus chemotherapy combined with immunotherapy for CLDN18.2-positive advanced solid tumors.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06350006
Study type Interventional
Source Shanghai Hengrui Pharmaceutical Co., Ltd.
Contact Wei Shi
Phone 0518-82342973
Email wei.shi@hengrui.com
Status Recruiting
Phase Phase 1
Start date May 30, 2024
Completion date December 30, 2028