Cystic Fibrosis and Non CF Bronchiectasis Clinical Trial
Official title:
The Role of Vitamin D3 in Pediatric Bronchiectasis Severity( CF Versus Non CF Bronchioectasis)
Vitamin D3 therapy was effective in decreasing the frequency of pulmonary exacerbations and preserving lung functions , thereby improving the disease severity even more in non CF than CF bronchiectasis patients
Objectives: To compare the effect of vitamin D3 on modifying the disease severity in CF and
non CF bronchiectasis pediatric patients.
Patients and Methods: This was a randomized clinical trial evaluating the role of oral
vitamin D3 supplementation for 6 months in forty patients with CF and non CF bronchiectasis
under the age of 18 years with vitamin D deficiency or insufficiency . The primary outcome
was to reach the sufficient Vitamin D level. The secondary outcome was to follow up the
frequency of pulmonary exacerbations and lung function after vitamin D3 supplementation.
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