Chemotherapy-induced Nausea and Vomiting Clinical Trial
Official title:
One Day Antiemetic Prophylaxis of NEPA (Netupitant Plus Palonosetron) and Dexamethasone to Prevent Chemotherapy-induced Nausea and Vomiting (CINV) in Breast Cancer Patients Receiving an AC-based Chemotherapy Regimen
This study evaluates if the activity of one-day of NEPA plus dexamethasone, to prevent chemotherapy-induced nausea and vomiting in breast cancer patients receiving adjuvant AC-based chemotherapy, is maintained during all the chemotherapy cycle treatment (maximum 4 cycles).
Patients included in the study should be treated with the following antiemetic prophylaxis,
during all the AC-based chemotherapy cycles, up to a maximum of 4 cycles:
- NEPA will be administered orally at the dose of 300 mg netupitant/0.5 palonosetron 1
hour before the start of any chemotherapy cycle.
- Dexamethasone 12 mg will be added on day 1 only of each cycle.
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