Condition: Abdominal Bone Flap Cranioplasty; Focus of Study: Perioperative Analgesia Clinical Trial
Official title:
Efficacy Of Scalp Block And Ultrasound Guided TAP Block With Clonidine As Adjuvant To Ropivacaine Versus Intravenous Fentanyl On Intraoperative Hemodynamics And Perioperative Analgesia In Abdominal Bone Flap Cranioplasties: A Prospective, Randomised, Double Blind Study
This study assesses efficacy of scalp block and Ultrasound guided transverse abdominis plane (TAP) block with 1µg/kg clonidine as adjuvant to 0.2% ropivacaine versus intravenous fentanyl (0.1µg/kg/hr) on intraoperative hemodynamics and perioperative analgesia in abdominal bone flap cranioplasties (ABFC).
Scalp blocks with local anaesthetic agents along with general anaesthesia provides
intraoperative and postoperative analgesia by blunting the hemodynamic responses to noxious
stimuli. The transversus abdominis plane "TAP" block, a regional anaesthesia technique that
provides analgesia following abdominal surgery. It involves a single large bolus injection of
local anaesthetic into an anatomical space between the internal oblique and transversus
abdominis muscles.
Ropivacaine is less cardio toxic, less arrhythmogenic, less toxic to central nervous system
(CNS) than bupivacaine, and it also has intrinsic vasoconstrictor property. Clonidine is an
alpha-2 receptor agonist, which has a known property of reducing requirement of analgesics in
the perioperative period.
This study aimed to assess the efficacy of scalp block and TAP block with 1µg/kg clonidine as
adjuvant to 0.2% ropivacaine versus intravenous fentanyl (0.1µg/kg/hr) on intraoperative
hemodynamics and perioperative analgesia in abdominal bone flap cranioplasties.
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