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Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy — Protocol S  

Proliferative Diabetic Retinopathy Clinical Trial

Official title:
Prompt Panretinal Photocoagulation Versus Intravitreal Ranibizumab With Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy

Clinical Trial Summary

The primary objective of the protocol is to determine if visual acuity outcomes at 2 years in eyes with proliferative diabetic retinopathy (PDR) that receive anti-vascular endothelial growth factor (anti-VEGF) therapy with deferred panretinal photocoagulation (PRP) are non-inferior to those in eyes that receive standard prompt PRP therapy. Secondary objectives include: - Comparing other visual function outcomes (including Humphrey visual field testing and study participant self-reports of visual function) in eyes receiving anti-VEGF with deferred PRP with those in eyes receiving prompt PRP. - Determining percent of eyes not requiring PRP when anti-VEGF is given in the absence of prompt PRP. - Comparing safety outcomes between treatment groups. - Comparing associated treatment and follow-up exam costs between treatment groups.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01489189
Study type Interventional
Source Jaeb Center for Health Research
Contact
Status Completed
Phase Phase 3
Start date March 2012
Completion date February 5, 2018
View Details
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